PreTect HPV-Proofer

PreTect HPV-Proofer is an assay for the qualitative detection of the presence of Human Papillomavirus, HPV, E6/E7 oncogene mRNA from carcinogenic HPV types 16, 18, 31, 33, 45.

PreTect HPV-Proofer is therefore a valuable tool to identify women with high risk of severe dysplasia.

This way the assay reduces unnecessary referral costs, and also psychological stress for the women concerned.




Clinical Benefits

  • Risk stratification and direct genotyping
  • E6/E7 mRNA expression from HPV 16, 18, 31, 33 and 45
  • Identifies cervical precursors most likely to progress to invasive cancers
  • Accurate patient management; Triaging HPV DNA positive women/Cytology
  • Enhances identification of cervical adenocarcinoma
  • Minimise unnecessary referral and over-treatment
  • Suitable even in young women


Test Information


*not included in kit
Individual HPV genotyping E6/E7 mRNA HPV 16, 18, 31, 33 and 45
Intrinsic Sample Control ISC): Targeting mRNA from housekeeping gene
Sample type: Cervical samples
Preservatives: PreTect TM (PreTect AS); PreservCyt; SurePath
Input-material: Isolated Nucleic Acid (DNA/RNA)*
Technology: Real time NASBA
  Isothermal amplification (41°C)
  Six specific molecular beacons
Format: 96-well PCR plate/strips Pre-filled with reagents
Assay time: ~ 150 minutes
Instrumentation: Fluorescence reader /
  RT-PCR (CFX-96/QuantStudio5)

Contact us

For more information about PreTect's products or ordering, please fill out the form below or send an email to