Cystatin C at IFCC EuroMedLab in Munich 2022

Learn more about cystatin C at booth #201

Gentian Diagnostics looks forward to exhibit at IFCC EuroMedLab in Munich April 2022 promoting our turbidimetric cystatin C immunoassay. Visit us at booth #201 to learn more about cystatin C.

Cystatin C - A superior kidney marker¹

Unique prognostic and diagnostic value of cystatin C:

• independent of muscle mass^2-8
• estimates GFR without race-adjustment⁹
• correlates well with GFR within the “creatinine blind area”¹⁰
• identifies chronic kidney disease (CKD) earlier than creatinine-based eGFR¹¹
• ensures safety and efficacy of medications with a narrow therapeutic index^9,12
  
  

Visit us at our booth #201 to learn more about cystatin C

Visit us during opening hours or book a meeting in advance through marketing@gentian.com. 

Gentian Cystatin C Immunoassay 

Gentian’s cystatin C immunoassay was launched in 2006. The assay is FDA510(k) cleared since 2008 and CE-marked. It is a Particle-Enhanced Turbidimetric Immunoassay (PETIA) for in vitro testing of cystatin C in human plasma and serum samples. The test has documented high inter-instrument accuracy on a wide range of clinical chemistry analysers.

Assay highlights

• Particle-Enhanced Turbidimetric Immunoassay
• With avian antibodies for reduced interference 
• Can be applied on most automated platforms
• ERM-DA471/IFCC standardised
• FDA510 (k) cleared and CE-marked

Contact us 

If you and your colleagues would like to learn more about cystatin C and how you could incorporate this test into clinical workflows within your organisation, please contact us via marketing@gentian.com or the form below:

References: 

1. Dharnidharka VR et al. Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis. Am J Kidney Dis. 2002
2. 1–226.KDIGO Guidelines 2012 published in Kidney International Supplements Vol3 Issue 1, Jan 2013
3. NCIC Clinical guideline (CG182) updated jan 2015 section 2.1 https://www.nice.org.uk/guidance/cg182/chapter/2-Implementation-getting-started.
4. Tangri N et al. Changes in dietary protein intake has no effect on serum cystatin C levels independent of the glomerular filtration rate. Kidney Int. 2011
5. Grubb A. Cystatin C is Indispensable for Evaluation of Kidney Disease. EJIFCC. 2017
6. Björk J  et al. Validation of standardized creatinine and cystatin C GFR estimating equations in a large multicentre European cohort of children. Pediatr Nephrol. 2019
7. Inker LA  et al. Estimating glomerular filtration rate from serum creatinine and cystatin C [published correction appears in N Engl J Med. 2012
8. Schaeffner ES et al. Two novel equations to estimate kidney function in persons aged 70 years or older. Ann Intern Med. 2012
9. Ebert N, Shlipak MG. Cystatin C is ready for clinical use. Curr Opin Nephrol Hypertens. 2020
10. Lindström V. Low molecular mass proteins as markers for renal function and dialysis efficiency. Doctoral Dissertation, Lund University, 2013.
11. Murty MS et al. Serum cystatin C as a marker of renal function in detection of early acute kidney injury. Indian J Nephrol. 2013
12. Frazee E et al. Cystatin C-Guided Vancomycin Dosing in Critically Ill Patients: A Quality Improvement Project. Am J Kidney Dis. 201