We look forward to Kidney Week 2023. Bring your questions regarding the biomarker cystatin C to booth #2016. Having worked with cystatin C assays since 2001, we are the experts on standardized (ERM-DA471/IFCC) turbidimetric cystatin C immunoassays.
Cystatin C is a superior glomerular filtration rate (GFR) marker for the diagnosis and therapeutic control of1,2:
Testing of cystatin C ensures an unbiased assessment of renal function, which is central to the diagnosis and management of CKD, as the biomarker is less susceptible to factors that influence muscle mass such as age, sex, race, physical activity, etc.3, 4
Based on input collected over 10 months from hundreds of patients, patient advocates, medical students, clinicians and scientists, the NKF-ASN Task Force: Reassessing the Inclusion of Race in Diagnosing Kidney Diseases published its final report on September 23, 2021, recommending "increased use of cystatin C combined with serum creatinine, as a confirmatory assessment of GFR or kidney function."
One key advantage of measuring cystatin C in addition to creatinine stems from the fact that cystatin C is less susceptible to factors that affect muscle mass (age, diet, race, sex, physical activity, etc.). Cystatin C is ubiquitously expressed through all nucleated cells. Individuals with similar kidney function can therefore be expected to have similar serum concentrations of cystatin C. This means that equations used for calculating GFR do not depend on an individual’s muscle mass or race.
Interested in more information about Gentian and our cystatin C assay? Please fill out the form below or send an email to marketing@gentian.com.