Cystatin C at ASN Kidney Week 2023

24. Oct 2023 | 5 min read

Cystatin C at ASN Kidney Week 2023

Visit the Cystatin C Company at Kidney Week at booth #2016

We look forward to Kidney Week 2023. Bring your questions regarding the biomarker cystatin C to booth #2016. Having worked with cystatin C assays since 2001, we are the experts on standardized (ERM-DA471/IFCC) turbidimetric cystatin C immunoassays. 

Cystatin C - A better estimated Glomerular Filtration Rate (eGFR) for all

Cystatin C is a superior glomerular filtration rate (GFR) marker for the diagnosis and therapeutic control of1,2:

  • Renal function
  • Kidney health
  • Chronic Kidney Disease (CKD)

Testing of cystatin C ensures an unbiased assessment of renal function, which is central to the diagnosis and management of CKD, as the biomarker is less susceptible to factors that influence muscle mass such as age, sex, race, physical activity, etc.3, 4

 

CTA-kidney-week-2023

 

Gentian's cystatin C immunoassay:

  • Developed and manufactured by Gentian
  • Open channel assay
  • Manufactured according to ISO 13485:2016
  • ERM-DA471/IFCC standardized
  • FDA510(k) cleared since 2008
  • IVDR-certified

 

Recommendation: Increased use of cystatin C

Based on input collected over 10 months from hundreds of patients, patient advocates, medical students, clinicians and scientists, the NKF-ASN Task Force: Reassessing the Inclusion of Race in Diagnosing Kidney Diseases published its final report on September 23, 2021, recommending "increased use of cystatin C combined with serum creatinine, as a confirmatory assessment of GFR or kidney function."

One key advantage of measuring cystatin C in addition to creatinine stems from the fact that cystatin C is less susceptible to factors that affect muscle mass (age, diet, race, sex, physical activity, etc.). Cystatin C is ubiquitously expressed through all nucleated cells. Individuals with similar kidney function can therefore be expected to have similar serum concentrations of cystatin C. This means that equations used for calculating GFR do not depend on an individual’s muscle mass or race. 

To learn more come visit our stand #2016

 

Get in touch for more information or book a meeting 

Interested in more information about Gentian and our cystatin C assay? Please fill out the form below or send an email to marketing@gentian.com

 

 

cystatin c immunoassay

 

References:

  1. Dharnidharka VR et al. Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis. Am J Kidney Dis, 2002
  2. Ebert N et al. Cystatin C is ready for clinical use. Curr Opin Nephrol Hypertens, 2020
  3. Tangri N et al. Changes in dietary protein intake has no effect on serum cystatin C levels independent of the glomerular filtration rate. Kidney Int, 2011
  4. Grubb, A. Cystatin C is Indispensable for Evaluation of Kidney Disease. Ejifcc, 2017

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