Webinar: The biomarker calprotectin - for plasma and serum

Biomarker for early detection of the inflammatory response to infections

Calprotectin is one of the earliest biomarkers for detection of the inflammatory response to infections^1,2. The biomarker is predominantly expressed in neutrophil granulocytes, and it is released upon neutrophil activation in response to inflammation and infection. 

Calprotectin in plasma and serum can be a valuable biomarker in different areas:

• discrimination between bacterial and viral infection³ 
• assessment of severe infections and sepsis^2,4,5
• prediction for development of severe infections⁶
• a risk marker in severe COVID-19^7,8
• for non-infectious inflammatory diseases, like rheumatic diseases⁹

Watch webinar: The biomarker calprotectin to learn more

Get in touch for information and ordering

Interested in calprotectin for plasma and serum? Want to know more? Please send an email to marketing@gentian.com or fill out the form below:

References:

1. Fullerton J et al. Kinetics of calprotectin, procalcitonin and C-reactive protein in healthy volunteers administered intravenous endotoxin. 40th International Symposium on Intensive Care & Emergency Medicine. Critical Care. 2020. P474.

2. Jonsson N et al. Calprotectin as an early biomarker of bacterial infections in critically ill patients: an exploratory cohort assessment. Crit Care Resusc. 2017.
3. Havelka A et al. Calprotectin, a new biomarker for diagnosis of acute respiratory infections. Sci Rep. 2020.
4. Larsson A et al. Calprotectin is superior to procalcitonin as a sepsis marker and predictor of 30-day mortality in intensive care patients. Scand J Clin Lab Invest. 2020.
5. Simm M et al. Performance of plasma calprotectin as a biomarker of early sepsis: a pilot study. Biomark Med. 2016.
6. Parke Å et al. Plasma-calprotectin compared with routine biomarkers for prediction of early severe event in sepsis. 40th International Symposium on Intensive Care & Emergency Medicine. Critical Care. 2020.
7. Bauer W et al. Outcome prediction by serum calprotectin in patients with COVID-19 in the emergency department. J Infect. 2021.
8. Luis García de Guadiana Romualdo et al. Circulating levels of GDF-15 and calprotectin for prediction of in-hospital mortality in COVID-19 patients: A case series. J Infect. 2021.
   
9. Ometto F et al. Calprotectin in rheumatic diseases. Exp Biol Med (Maywood). 2017.