WEBINAR: Cystatin C , Creatinine and eGFR Equations

Cystatin C Webinar Series: CKD-EPI equations

Cystatin C is a superior glomerular filtration rate (GFR) marker for the diagnosis and therapeutic control of renal function¹, kidney health² and Chronic Kidney Disease (CKD). In our Cystatin C webinar series we are now preparing four webinars where we discuss the benefits of cystatin C testing and why the combination of cystatin C and creatinine gives a significant advantage in kidney health and CKD. 

In the first webinar Gaute Tangen, Global Product Manager, will talk about the biomarkers Cystatin C and Creatinine in relation to eGFR equations.

A better estimated Glomerular Filtration Rate (eGFR) for all

Cystatin C testing ensures an unbiased assessment of renal function, which is central to the diagnosis and management of chronic kidney disease (CKD). The biomarker has far-reaching benefits across all patient groups, but certain patient populations may experience more benefits. This relates specifically to children, amputees and elderly. These patient groups can receive more accurate eGFRs with testing of cystatin C because cystatin C is less susceptible to factors that influence muscle mass such as age, sex, race, physical activity, etc.^{3, 4}

Clinical use of cystatin C is recommended in guidelines published by KDIGO.⁵ In the US, a joint task force assembled by the National Kidney Foundation (NKF) and the American Society of Nephrology (ASN) has also recommended increased use of cystatin C in combination with creatinine to confirm eGFR and support clinical decision-making.⁶

Watch webinar: Cystatin C , Creatinine and eGFR Equations

In this webinar you will learn more about:

• Disparities in kidney care
• Cystatin C for earlier diagnosis of CKD
• The recommendation to remove the race factor from creatinine equations
• The ideal combination of the two biomarkers cystatin C and creatinine

Watch on YouTube

Gentian’s turbidimetric and open access cystatin C immunoassay

Gentian Cystatin C Immunoassay is applied to turbidimetry-based clinical chemistry platforms. It is an open channel assay, meaning it can be added to all clinical chemistry analysers.

• FDA510(k) cleared since 2007
• CE-marked and IVDR certified
• Developed and manufactured by Gentian Diagnostics
• Manufactured according to ISO 13485:2016
  
  

Contact us for more information and ordering

Explore cystatin C in your laboratory - fill out the form or send an email to marketing@gentian.com for more information about the product and prices.

References:

1. Dharnidharka VR et al. Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis. Am J Kidney Dis, 2002
2. Ebert N et al. Cystatin C is ready for clinical use. Curr Opin Nephrol Hypertens, 2020
3. Tangri N et al. Changes in dietary protein intake has no effect on serum cystatin C levels independent of the glomerular filtration rate. Kidney Int, 2011
4. Grubb, A. Cystatin C is Indispensable for Evaluation of Kidney Disease. Ejifcc, 2017
5. 2012, KG, Kidney International Supplements Vol3
6. Miller WG et al. National Kidney Foundation Laboratory Engagement Working Group Recommendations for Implementing the CKD-EPI 2021 Race-Free Equations for Estimated Glomerular Filtration Rate: Practical Guidance for Clinical Laboratories. Clin Chem, 2022

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