GCAL® Calprotectin – A new standard in inflammation testing
At EuroMedLab 2025 in Brussels, Gentian Diagnostics will highlight GCAL®, our IVDR-certified (CE 0123) calprotectin assay designed for plasma and serum samples, that redefines how inflammation is measured and monitored. As demand rises for rapid, actionable inflammation diagnostics, GCAL® delivers both clinical impact and seamless integration into laboratory workflows.
Visit the Gentian GCAL® team at booth #115
Calprotectin (S100A8/A9) in rheumatic diseases
Gain insight of the patients’ inflammation status from one standard blood test:
- Calprotectin (S100A8/A9): Inclusion of calprotectin measurements in guidelines issued by EULAR, ACR, and PReS1
- Directly reflecting local joint inflammatory activity: Assess patients’ treatment response2,3
- Sensitive marker even for subclinical disease activity: Distinguish true immunological remission4,5
- Risk marker for disease flares: Guide for treatment decisions4,7
- Marked elevation in systemic Juvenile idiopathic arthritis (JIA): Strongly supports diagnosis of Still’s disease1,8
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GCAL®: The first turbidimetric assay for measuring circulating calprotectin
Gentian GCAL® Calprotectin immunoassay is designed for the quantitative determination of calprotectin in plasma and serum, intended as an aid in detection and assessment of inflammation and inflammatory response to infections.
GCAL® offers accurate, versatile, and rapid diagnostic capabilities, all while integrating smoothly into existing lab workflows for streamlined efficiency:
- Advanced technology: PETIA assay on clinical chemistry platforms using avian antibodies, which minimises interference from rheumatoid factor and HAMA antibodies
- Versatility: Open channel and compatible with a wide range of automated clinical chemistry analysers
- Regulatory compliance: CE-marked in compliance with IVDR 2017/746 (CE 0123), and registered in multiple regions*
- Ready-to-use format: Complete kit components - including calibrators and dedicated controls - are available in two sizes to meet the needs of both small and high-volume laboratories

Visit Gentian at Booth #115
Focusing on acute care, chronic inflammation, or expanding your lab’s biomarker offerings? Join us at EuroMedLab 2025 to discover how GCAL® is redefining inflammation diagnostics. The Gentian team will be available at booth#115 to demonstrate the assay, share new clinical data, and explore how GCAL® can add value to your lab's test menu.
Get in touch
Explore GCAL® in your lab - fill out the form or send an email to marketing@gentian.com for more information about the product and prices.
References:
1. Fautrel B et al. Ann Rheum Dis. 2024
2. Pruenster M et al. Pharmacol Ther. 2016
3. Anink J et al. Arthritis Res Ther. 2015
4. La C et al. RMD Open. 2021
5. Foell D et al. JAMA. 2010
6. Sumner EJ et al. Clin Rheumatol. 2022
7. Inciarte-Mundo J et al. Arthritis Res Ther. 2018
8. Park C et al. Rheumatology (Oxford). 2022
*This website may contain information about products that are not registered for use in your country of residence and may not comply with applicable laws or regulations in that country. We do not take any responsibility for accessing such information in those circumstances.