News about Shrunken Pore Syndrome (SPS) and Cystatin C

28. Sep 2020 | 5 min read

News about Shrunken Pore Syndrome (SPS) and Cystatin C

We hope you have had the chance to watch the successful AACC webinar The Use of Biomarkers in Chronic Kidney Disease and the Novel Disorder Shrunken Pore Syndrome with Dr. Anders Grubb. In this webinar Dr. Grubb is discussing using creatinine and  cystatin C to diagnose Shrunken Pore Syndrome (SPS).


Cystatin C and creatinine together diagnose SPS

Dr. Grubb and his colleagues described SPS for the first time in an article in Scandinavian Journal of Clinical and Laboratory Investigation in 2015. In the AACC CLN Stat article To Catch Shrunken Pore Syndrome, Measure Cystatin C from July 2020, Dr. Grubb states that both cystatin C and creatinine are needed to diagnose SPS.  Dr. Grubb therefore recommends to include the determination of cystatin C in the KDIGO guidelines which are from 2012, three years before SPS was discovered. 


New articles about shrunken pore syndrome (SPS)

Since the launch of the webinar September 2019 more studies have been published regarding the novel shrunken pore syndrome (SPS):


Webinar: Gentian Cystatin C Immunoassay

Want to know more about Gentian’s Cystatin C Immunoassay? Watch this webinar with Gentian’s Product Manager for Cystatin C, Gaute Tangen.


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More information about cystatin C?

For more details on cystatin C in general or the Gentian Cystatin C Immunoassay please contact us at or fill out the form below:


Shrunken Pore Syndrome (SPS) on Wikipedia 

Shrunken pore syndrome is now described on Wikipedia both in English and in Swedish:

Cystatin C immunoassay brochure

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