Glycosylation of NT-proBNP: What clinicians and laboratories need to know
NT-proBNP plays a critical role in the diagnosis and management of heart failure, yet important biological and analytical factors can influence how this biomarker is measured and interpreted. One of the most significant factors is endogenous glycosylation of the NT-proBNP molecule.
The upcoming webinar Glycosylation of NT-proBNP: What clinicians and laboratories need to know brings together two leading experts to explain how NT-proBNP glycosylation affects clinical practice and laboratory testing, and why it matters for patient care. Join this expert led session to deepen your understanding of NT-proBNP glycosylation and its relevance for everyday clinical and laboratory practice.
Key learning objectives
By linking real world clinical use with insights into NT-proBNP biology, this webinar will help clinicians and laboratory professionals better understand factors that influence NT-proBNP measurement and interpretation:
- A clear overview of how NT-proBNP is currently used in heart failure care, and where challenges remain in real-world clinical decision-making
- An understanding of NT-proBNP glycosylation at the molecular level, and how it can interfere with antibody-based immunoassays
- Insight into analytical variability in NT-proBNP testing, including why measured concentrations may be systematically underestimated in some assays
- Practical considerations for clinicians and laboratories seeking greater analytical consistency across platforms and patient populations
Expert speakers

Dr. Peder Myhre, Professor of Cardiology, will discuss the clinical role of NT-proBNP, highlighting unmet needs and unresolved challenges in heart failure diagnostics.
Dr. Robert Christenson, Professor of Pathology, will explore the biology of NT-proBNP glycosylation and its implications for assay performance in the laboratory.

About Gentian’s NT-proBNP development
Gentian’s ongoing development of open channel clinical chemistry glycosylation-independent NT-proBNP assay represents an important step toward more reliable heart failure diagnostics. Ongoing analytical and clinical studies aim to further clarify the impact of glycosylation and demonstrate improved diagnostic performance while enabling broader access via open clinical chemistry platforms.
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Interested in Gentian’s NT-proBNP work?
Interested in Gentian’s NT-proBNP development or open-access clinical chemistry solutions? Get in touch to learn more: marketing@gentian.com or fill out the form: